compound introduction
FdUMP (triethylammonium) 是 5-氟尿嘧啶 (5-FU) 的细胞内活性形式。5-FU 转运进入细胞后在多种酶的作用下转化为FdUMP。FdUMP 与胸苷酸合成酶 (thymidylate synthetase) 及其辅因子5,10-亚甲基四氢叶酸 (5,10-methylene tetrahydrofolate) 形成三元配合物抑制胸苷酸合成酶活性，进而导致 DNA 合成被抑制。
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Fluorodeoxyuridylate
CAS number：134-46-3 molecular formula：C9H12FN2O8P
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 134-46-3 | molecular formula | C9H12FN2O8P |
| molecular weight | 326.170 g/mol | Exact mass | ≥99% |
| PSA | 146.000 Ų | logp | -2.8 |
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