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2-(chloromethyl)-6-(4-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

CAS number:851398-76-0    molecular formula:C13H8Cl2N2OS

overview

compound introduction

N6F11 是一种选择性铁死亡 (ferroptosis) 诱导剂,可以通过靶向 TRIM25 介导的GPX4降解,选择性地诱导癌细胞发生铁死亡 (ferroptosis),同时对免疫细胞没有影响。N6F11 启动了依赖 HMGB1 的肿瘤免疫,由 CD8+T 细胞介导。

Specs

Chinese alias-
English alias-
CAS number851398-76-0molecular formulaC13H8Cl2N2OS
molecular weight311.2 g/molExact mass≥98%
PSA69.700 Ųlogp3.6

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