compound introduction
E7820 (ER68203-00) 是一种芳香族磺酰胺衍生物，是一种独特的血管生成 (angiogenesis) 抑制剂，可抑制内皮上整合素 α2 (integrin alpha2) 亚基的表达。E7820 抑制大鼠主动脉血管生成，IC50 为 0.11 μg/ml。E7820 调节 α-1，α-2，α-3 和 α-5 整联素 mRNA 表达。具有抗血管生成和抗肿瘤活性。
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E 7820
CAS number：289483-69-8 molecular formula：C17H12N4O2S
overview
Specs
| Chinese alias | 3-氰基-N-(3-氰基-4-甲基-1H-吲哚-7-基)苯磺酰胺 | ||
| English alias | DTXSID20183142 | LWGUASZLXHYWIV-UHFFFAOYSA-N | T2402 | 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide | AC-36189 | HY-113248 | O6M | HY-14571 | Q27290435 | s3838 | FT-0714239 | 8-N-Boc-5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-propoinicacid | F2 | ||
| CAS number | 289483-69-8 | molecular formula | C17H12N4O2S |
| molecular weight | 336.37 g/mol | Exact mass | 10mM in DMSO |
| PSA | 118.000 Ų | logp | 2.4 |
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MSDS
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289483-69-8 | E7820.pdf
