compound introduction
FRAX486 是一种 PAK抑制剂，对 PAK1，PAK2 和 PAK3 的 IC50 值分别为 14，33 和 39 nM
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FRAX 486
CAS number：1232030-35-1 molecular formula：C25H23Cl2FN6O
overview
Specs
| Chinese alias | - | ||
| English alias | FRAX486 | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, FRAX 486, FRAX-486, 6-(2,4-Dichlorophenyl)-8-ethyl-2-(3-fluoro-4-(piperazin-1-yl)phenylamino)pyrido[2,3-d] pyrimidin-7(8H)-one | 6-(2,4-d | ||
| CAS number | 1232030-35-1 | molecular formula | C25H23Cl2FN6O |
| molecular weight | 513.39 g/mol | Exact mass | - |
| PSA | 73.400 Ų | logp | 4.800 |
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