5（S），15（S）-DiHETE是在人嗜酸性粒细胞中生物合成的。它已显示出可增强嗜中性粒细胞的脱粒作用，并能作为人类嗜酸性粒细胞的有效趋化因子。 5(S),15(S)-DiHETE is biosynthesised in human eosinophils. It has shown to enhance neutrophil degranulation and serve as a potent chemotaxin for human eosinophils 5(S),15(S)-DiHETE is supplied as a solution in ethanol.To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. Solvents such as DMSO and dimethyl formamide purged with an inert gas can be used. The solubility of 5(S),15(S)-DiHETE in these solvents is approximately 50 mg/ml. 5(S),15(S)-DiHETE is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, the ethanolic solution of 5(S).15(S)-DiHETE should be diluted with the aqueous buffer of choice. The solubility of 5(S),15(S)-DiHETE in PBS (pH 7.2) is approximately 1 mg/ml. We do not recommend storing the aqueous solution for more than one day. .
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5(S),15(S)-DiHETE
CAS number：82200-87-1 molecular formula：C20H32O4
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (5S,6E,8Z,11Z,13E,15S)-5,15-dihydroxyicosatetraenoic acid | 5(S),15(S)-Dihydroxy-6,13-trans-8,11-cis-eicosatetraenoic acid | 6,8,11,13-Eicosatetraenoic acid, 5,15-dihydroxy-, (5S,6E,8Z,11Z,13E,15S)- | SR-01000946935-1 | (5S,6E,8Z,11Z,13E,15S)-5,15-dihydro | ||
| CAS number | 82200-87-1 | molecular formula | C20H32O4 |
| molecular weight | 336.47 g/mol | Exact mass | ≥98% |
| PSA | 77.800 Ų | logp | 4 |
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