CAS number：1330180-22-7 molecular formula：C13H7D5N2O5S
Nimesulide-d5 是 Ethacrynic acid 的氘代物。Nimesulide 是一种有选择性的 COX-2 抑制剂，对其抑制具有时间依赖性，IC50 值为 70 nM-70 μM，但对 COX-1 的作用较弱 (IC50 >100 μM)。 Nimesulide 具有抗炎、止痛、解热的作用。 Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties。
| Chinese alias | - | ||
| English alias | Aulin-d5 | Flogovital-d5 | 4′-Nitro-2′-(phenoxy-d5)methanesulfonanilide | N-(4-Nitro-2-(phenoxy-d5)phenyl)methanesulfonamide | ||
| CAS number | 1330180-22-7 | molecular formula | C13H7D5N2O5S |
| molecular weight | 313.34 g/mol | Exact mass | ≥98%,≥98atom%D |
| PSA | 110.000 Ų | logp | 2.6 |
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