All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

Navarixin (SCH-527123)

CAS number:473727-83-2    molecular formula:C21H23N3O5

overview

compound introduction

Information Navarixin (SCH-527123) Navarixin (SCH-527123, MK-7123, PS-291822) is a potent, orally bioavailable CXCR2/CXCR1 antagonist with IC50 values of 2.6 nM and 36 nM, respectively. Targets CXCR2 (Cell-free assay); CXCR1 (Cell-free assay) 2.6 nM; 36 nM

Specs

Chinese alias-
English aliasMK-7123 | PS-291822Benzamide,2-​hydroxy-​N,​N-​dimethyl-​3-​[[2-​[[(1R)​-​1-​(5-​methyl-​2-​furanyl)​propyl]​amino]​-​3,​4-​dioxo-​1-​cyclobuten-​1-​yl]​amino]​-
CAS number473727-83-2molecular formulaC21H23N3O5
molecular weight397.42 g/molExact mass-
PSA112.000 Ųlogp1.635

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

No safety information yet

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 0 shareMSDS