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RS 102895 hydrochloride

CAS number:1173022-16-6    molecular formula:C21H22ClF3N2O2

overview

compound introduction

RS102895 hydrochloride 是一种有效的 CCR2 拮抗剂,IC50 值为 360 nM,对 CCR1 无作用。 作用:RS-102895 hydrochloride 还可抑制细胞中的 human α1a 和 α1d receptors,大鼠脑皮质 5-HT1a receptor,其IC50值分别为130 nM、320 nM和470 nM。

Specs

Chinese alias1'-[2-[4-(三氟甲基)苯基]乙基]螺[4H-3,1-苯并恶嗪-4,4'-哌啶]-2(1H)-盐酸盐
English alias1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one HCl | AKOS024456940 | 1'-{2-[4-(Trifluoromethyl)phenyl]ethyl}spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one--hydrogen chloride (1/1) | BCP18408 | RS-102895 HCl | 1
CAS number1173022-16-6molecular formulaC21H22ClF3N2O2
molecular weight426.9 g/molExact mass≥98%
PSA41.600 Ųlogp-

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