RS102895 hydrochloride 是一种有效的 CCR2 拮抗剂,IC50 值为 360 nM,对 CCR1 无作用。 作用:RS-102895 hydrochloride 还可抑制细胞中的 human α1a 和 α1d receptors,大鼠脑皮质 5-HT1a receptor,其IC50值分别为130 nM、320 nM和470 nM。
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RS 102895 hydrochloride
CAS number:1173022-16-6 molecular formula:C21H22ClF3N2O2
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Specs
| Chinese alias | 1'-[2-[4-(三氟甲基)苯基]乙基]螺[4H-3,1-苯并恶嗪-4,4'-哌啶]-2(1H)-盐酸盐 | ||
| English alias | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one HCl | AKOS024456940 | 1'-{2-[4-(Trifluoromethyl)phenyl]ethyl}spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one--hydrogen chloride (1/1) | BCP18408 | RS-102895 HCl | 1 | ||
| CAS number | 1173022-16-6 | molecular formula | C21H22ClF3N2O2 |
| molecular weight | 426.9 g/mol | Exact mass | ≥98% |
| PSA | 41.600 Ų | logp | - |
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