CAS number：2244881-69-2 molecular formula：C17H20N2O4
C-171 是干扰素基因刺激物 (STING) 的抑制剂。 它与 STING 结合，抑制其棕榈酰化，并阻止 TBK1 的募集和磷酸化。 C-171 is a covalent small-molecule inhibitor of STING. C-171 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING.
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| CAS number | 2244881-69-2 | molecular formula | C17H20N2O4 |
| molecular weight | 316.35 g/mol | Exact mass | ≥98% |
| PSA | 88.100 Ų | logp | 5.3 |
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