CCX354 is an antagonist of CCR1 , with anti-inflammatory activity. In Vitro CCX354 shows potent activities in the chemotaxis assay, with IC 50 In Vivo In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CCR1
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CCX354
CAS number:1010073-75-2 molecular formula:C22H22ClN7O2
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| Chinese alias | - | ||
| English alias | ZIMLRKWQDLVPEK-UHFFFAOYSA-N | CCR1 antagonist 1 | MS-28213 | 1359144-02-7 | GSK2941266 | GSK-2941266 | SCHEMBL1638749 | 1010073-75-2 | CCX354 | CCX-354 | Ethanone, 1-(4-(4-chloro-3-methoxyphenyl)-1-piperazinyl)-2-(3-(1H-imidazol-2-yl)-1H-pyrazolo(3,4-b)py | ||
| CAS number | 1010073-75-2 | molecular formula | C22H22ClN7O2 |
| molecular weight | 451.91 g/mol | Exact mass | ≥98% |
| PSA | 92.200 Ų | logp | 2.5 |
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