compound introduction
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC 50 of 6.8 nM in calcium flux assay In Vitro CCR1 antagonist 9 (Compound 19e) blocks the CCR1 chemotaxis of THP-1 cells with an IC 50 of 28 nM. CCR1 antagonist 9 also blocks hERG with an IC 50 of 30 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CCR1 6.8 nM (IC 50 , in calcium flux assay)
