TPO agonist 1 is a thrombopoietin (TPO) agonist extracted from patent WO2008134338A1, compound TPO mimetic. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia In Vivo The thrombopoietin (TPO) receptor agonists are novel treatments for patients with chronic ITP aimed at increasing platelet production through interactions with the TPO receptor on megakaryocytes, and can increases platelet counts, decrease bleeding events and reduce the need for adjunctive or rescue treatments. The TPO receptor agonists are well-tolerated, though uncertainty remains regarding the risk of thromboembolism and bone marrow fibrosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TPO receptor
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TPO agonist 1
CAS number：1033040-23-1 molecular formula：C25H22N8O2
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| Chinese alias | TPO 激动剂 1 | ||
| English alias | PD118142 | LGD-4665 | SCHEMBL164331 | A907797 | AKOS040742770 | SCHEMBL13477376 | TPO agonist 1 | SB-559448 | 2-(3,4-dimethylphenyl)-4-[[2-hydroxy-3-[3-(2H-tetrazol-5-yl)phenyl]phenyl]diazenyl]-5-methyl-1H-pyrazol-3-one | HY-100380 | 1033040-23-1 | MS-285 | ||
| CAS number | 1033040-23-1 | molecular formula | C25H22N8O2 |
| molecular weight | 466.49 g/mol | Exact mass | ≥98% |
| PSA | 132.000 Ų | logp | 5 |
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