Xanthomicrol 是从菝葜 (玄参科) 的树脂中提取的,是单胺氧化酶 (MAOs) 抑制剂。Xanthomicrol 有抗肿瘤活性和抗炎活性,在 HL60,K562 细胞中的IC50为 0.88,1.69 μg/mL。Xanthomicrol 是 5DT 在小鼠结肠中的主要代谢物,可降低iNOS蛋白和mRNA水平以及COX-2蛋白水平,还能降低促炎细胞因子IL-1β的产生,诱导抗氧化酶HO-1的表达。
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Xanthomicrol
CAS number:16545-23-6 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 16545-23-6 | molecular formula | |
| molecular weight | 344.300 g/mol | Exact mass | - |
| PSA | 94.500 Ų | logp | 2.9 |
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