Description Introduction of 4-sulfo-phenylalanine is an effective strategy for increasing solubility of a peptide. This amino acid has also been employed in analogs of angiotensin 2 [1], phytosulfokine [2], and cyclolinopeptide A [3]. Its incorporation during solid phase synthesis using Fmoc-Phe(SO3Na)-OH is best carried out with base-mediated coupling methods such as PyBOP®or HBTU. Description Introduction of 4-sulfo-phenylalanine is an effective strategy for increasing solubility of a peptide. This amino acid has also been employed in analogs of angiotensin 2 [1], phytosulfokine [2], and cyclolinopeptide A [3]. Its incorporation during solid phase synthesis using Fmoc-Phe(SO3Na)-OH is best carried out with base-mediated coupling methods such as PyBOP®or HBTU.
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Fmoc-Phe(SO3Na)-OH
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| Chinese alias | - | ||
| English alias | Fmoc-Phe(SO3Na)-OH, N-α-Fmoc-4-sulfophenylalanine sodium salt | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | Reagent Grade |
| PSA | - | logp | - |
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