C-6 NBD神经酰胺是短链膜可渗透神经酰胺的生物活性荧光类似物。它在抑制病毒糖蛋白通过高尔基体转运方面与C-6神经酰胺一样有效。1C-6 NBD神经酰胺已被用作UDP-葡萄糖：神经酰胺葡糖基转移酶2活性的荧光底物，并证明了葡萄糖脑苷脂的转运3 C-6 NBD-二氢-神经酰胺在结构上与C-6 NBD神经酰胺没有区别，只是它在鞘氨醇主链的C-4 / C-5位置含有一个饱和键。 C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1 C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2 and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3 C-6 NBD-dihydro-Ceramide is structurally indistinguishable to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.
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C-6 NBD-dihydro-Ceramide
CAS number：114301-95-0 molecular formula：C30H51N5O6
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Specs
| Chinese alias | - | ||
| English alias | N-(1,3-DIHYDROXYOCTADECAN-2-YL)-6-[(7-NITRO-2,1,3-BENZOXADIAZOL-4-YL)AMINO]HEXANAMIDE | N-(1,3-dihydroxyoctadecan-2-yl)-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide | C-6 NBD-dihydro-Ceramide | J-003078 | DTXSID90693945 | ||
| CAS number | 114301-95-0 | molecular formula | C30H51N5O6 |
| molecular weight | 577.76 g/mol | Exact mass | - |
| PSA | - | logp | - |
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