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Chondroitinase ABC from Proteus vulgaris

CAS number:unknown    molecular formula:

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Degradation of Chondroitin sulfate-containing tissue such as extracellular matrices and cartilageNeural regeneration researchEliminative degradation of all forms of Chondroitin sulfate: A, B and CQuantitation of glucosaminoglycans (mucopolysaccharides)应用: Chondroitinase ABC is a lyase with specificity toward chondroitin sulfates and dermatan sulfates - with some minor activity toward hyaluronan. This recombinant version only contains the endolytic chondroitinase, meaning it will not digest the non-reducing ends of proteoglycan substrates. It targets β-(1,4)-linkages between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid. The product of digestion is a mixture of Δ 4-unsaturated tetra- and di-saccharides. Chondroitinase ABC is a lyase with specificity toward chondroitin sulfates and dermatan sulfates - with some minor activity toward hyaluronan. This recombinant version only contains the endolytic chondroitinase, meaning it will not digest the non-reducing ends of proteoglycan substrates. It targets β-(1,4)-linkages between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid. The product of digestion is a mixture of Δ 4-unsaturated tetra- and di-saccharides. Application: Degradation of Chondroitin sulfate-containing tissue such as extracellular matrices and cartilage Neural regeneration research Eliminative degradation of all forms of Chondroitin sulfate: A, B and C Quantitation of glucosaminoglycans (mucopolysaccharides)

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