PHA-665752 hydrate has been used as a c-Met inhibitor: to study its effects on oxidative stress in human mammary epithelial MCF10A cells with extra centrosomes to study its effects on the clonogenicity of T-cell specific transcription factor/ lymphoid enhancer-binding factor-1 (TCF/LEF-1) responsive promoter to drive expression of green fluorescent protein (TOP-GFP) cancer stem cell (CSC) cultures to study its inhibitory effects on melanoma cell lines
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PHA-665752
CAS number:477575-56-7 molecular formula:C32H34Cl2N4O4S
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| Chinese alias | - | ||
| English alias | PHA-665752 hydrate | (3Z)-5-{[(2,6-dichlorophenyl)methane]sulfonyl}-3-[(3,5-dimethyl-4-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one | 2H-Indol-2-one, 5-(((2,6-dichlorophenyl)methyl)sulfon | ||
| CAS number | 477575-56-7 | molecular formula | C32H34Cl2N4O4S |
| molecular weight | 641.61 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 5.000 |
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