CAS number：1121931-70-1(DMSO) molecular formula：C23H29N3O3
CM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice.
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| CAS number | 1121931-70-1(DMSO) | molecular formula | C23H29N3O3 |
| molecular weight | 395.49 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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