compound introduction
Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor ( NNRTI ), with an IC 50 of 0.3 µM for reverse transcriptase from HIV-1 . Loviride (R 89439) inhibits HIV-1 , HIV-2 and SIV replication in MT-4 cells In Vitro Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC 50 s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.3 µM (Reverse transcriptase)
