compound introduction
DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC 50 value of 17.9 µM. DCLX069 shows less active against PRMT4 and PRMT6 . DCLX069 has anticancer effects In Vitro DCLX069 (12.5-100 µM) effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid leukemia cell lines (MCF7, HepG2, and THP1 cells) in a concentration-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PRMT1 17.9 μM (IC 50 )
