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(S)-Ceralasertib

CAS number:1352226-87-9(DMSO)    molecular formula:C20H24N6O2S

overview

compound introduction

(S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC 50 of 2.578 nM.(S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics.(S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition .

Specs

Chinese alias(S)-塞拉拉塞特
English alias-
CAS number1352226-87-9(DMSO)molecular formulaC20H24N6O2S
molecular weight412.51 g/molExact mass10mM in DMSO
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