compound introduction
PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1) , with no effect on PTH type 2 receptor. In Vitro PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 induces cAMP production with an EC 50 of 2.4 μM in COS-7 cells expressing hPTHR1, and 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC 50 , 17 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PTHR1
