compound introduction
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC 50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC 50 of 11.5 μM SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity . In Vitro SIRT1-IN-1 (compound 2) has little effect on SIRT3 (IC 50 >100 μM) and HDAC (IC 50 >100 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:SIRT1 0.205 μM (IC 50 ) SIRT2 11.5 μM (IC 50 ) SIRT3 >100 μM (IC 50 )
