compound introduction
SGC3027 is a histone methyltransferase inhibitor SGC3027 is the first potent, selective and cell active chemical probe for PRMT7 . In Vitro SGC3027 is a pro-drug of SGC8158 which releases the active component upon reduction in the cell by reductases.? In cellular assays using C2C12 cells, SGC3027 inhibits the methylation of HSP70 with IC 50 =1.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PRMT7
