CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a CB1/CB2 (cannabinoid receptor) competitive agonist. CB1/2 agonist 3 acts on hCB1 and hCB2 with K i values of 5.9 nM and 3.5 nM, respectively . Form:Solid IC50& Target:hCB1-R 5.9 nM (Ki) hCB2-R 3.5 nM (Ki) In Vitro:CB1/2 agonist 3 (compound 52) can partially induce [ 35 S]GTPγS binding to hCB1-CHO cell membranes with an EC 50 value of 30.99 nM, and slightly inhibit [ 35 S]GTPγS binding to hCB2-CHO cell membranes with a mean EC 50 value of 1.28 nM . CB1/2 agonist 3 (compound 52) ((1 μM, 1 h) has antagonistic effect on CB1/CB2 agonist CP-55940 with a K b value of 78.17 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
CB1/2 agonist 3
CAS number：2772655-86-2 molecular formula：C25H41NO2
overview
compound introduction
Specs
| Chinese alias | CB1/2 激动剂 3 | ||
| English alias | - | ||
| CAS number | 2772655-86-2 | molecular formula | C25H41NO2 |
| molecular weight | 387.60 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
