ARL67156 (FPL 67156) trisodium hydrate is a selective ecto-ATPase inhibitor. ARL67156 trisodium hydrate is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12 μM, respectively. ARL67156 trisodium hydrate can be used Appearance:Solid IC50& Target:Ki: 11 μM (NTPDase1), 18 μM (NTPDase3), 12 μM (NPP1) In Vitro:ARL67156 trisodium hydrate (1-100 μM) potentiates neurogenic contractions in a concentration-dependent manner. ARL67156 trisodium hydrate (10 μg/mL, 24 h) increases the surface expression of CXCR3 on ATP-treated HMC-1 cells. ARL67156 trisodium h In Vivo:ARL67156 trisodium hydrate (1.1 μg/kg/day, administered with osmotic pumps implanted subcutaneously, for 28 days) prevents the development of calcific aortic valve disease in Warfarin (HY-B0687)-treated rats. ARL67156 trisodium hydrate (intraperitone Biological Activity:ARL67156 (FPL 67156) trisodium hydrate is a selective ecto-ATPase inhibitor. ARL67156 trisodium hydrate is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12u2009μM, respectively. ARL67156 trisodium hydrate can be u
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ARL67156 trisodium hydrate
CAS number：unknown molecular formula：C15H23Br2N5Na3O13P3
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| Chinese alias | ARL67156 三钠水合物 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C15H23Br2N5Na3O13P3 |
| molecular weight | 834.61 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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