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DC-BPi-11 hydrochloride

CAS number:2758411-61-7(free basis)    molecular formula:

overview

compound introduction

DC-BPi-11 hydrochloride 是溴域 PHD 指转录因子 (BPTF) 的抑制剂,IC50 为 698 nM。DC-BPi-11 hydrochloride 对白血病细胞增殖有显著抑制作用。 DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation. Appearance:Solid IC50& Target:698 nM (BPTF) In Vitro:DC-BPi-11 hydrochloride (0.1 nM-1 μM; 24 h) inhibits BPTF in human leukemia MV-4-11 cells with an EC 50 value of 120 nM. DC-BPi-11 hydrochloride (0.01 μM-100 μM; 24 h) significantly inhibits the proliferation of human leukemia MV-4-11 cells (IC 50 =0 Biological Activity:DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation.

Specs

Chinese aliasDC-BPi-11盐酸盐
English alias-
CAS number2758411-61-7(free basis)molecular formula
molecular weight-Exact mass≥97%
PSA-logp-

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