DC-BPi-11 hydrochloride 是溴域 PHD 指转录因子 (BPTF) 的抑制剂,IC50 为 698 nM。DC-BPi-11 hydrochloride 对白血病细胞增殖有显著抑制作用。 DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation. Appearance:Solid IC50& Target:698 nM (BPTF) In Vitro:DC-BPi-11 hydrochloride (0.1 nM-1 μM; 24 h) inhibits BPTF in human leukemia MV-4-11 cells with an EC 50 value of 120 nM. DC-BPi-11 hydrochloride (0.01 μM-100 μM; 24 h) significantly inhibits the proliferation of human leukemia MV-4-11 cells (IC 50 =0 Biological Activity:DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC 50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation.
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DC-BPi-11 hydrochloride
CAS number:2758411-61-7(free basis) molecular formula:
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| Chinese alias | DC-BPi-11盐酸盐 | ||
| English alias | - | ||
| CAS number | 2758411-61-7(free basis) | molecular formula | |
| molecular weight | - | Exact mass | ≥97% |
| PSA | - | logp | - |
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