ACTH (1-17) TFA, an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a K i of 0.21 nM. Appearance:Solid IC50& Target:MC1R In Vitro:ACTH (1-17) TFA is a potent agonist at the hMC1R. ACTH (1-17) shows high affinity for the hMC1R with a K i value of 0.21±0.03 nM which is slightly higher than that of 0.13±0.005 nM for alpha-MSH. ACTH (1-17) induces a slight and not significant incre In Vivo:Inhibition of DNA labeling is noted when the ACTH (1-17) is administered at 2 hr after the beginning of the daily dark span when nocturnal animals become active. When administered at this circadian stage, the larger dose in particular is associated with a Biological Activity:ACTH (1-17) TFA, an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a K i of 0.21 nM.
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ACTH (1-17) (TFA)
CAS number:unknown molecular formula:C95H145N29O23S.C2HF3O2
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| Chinese alias | 促肾上腺皮质激素 (1-17) (三氟乙酸) | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C95H145N29O23S.C2HF3O2 |
| molecular weight | 2207.43 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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