FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research. Appearance:Solid IC50& Target:K D : 20 nM (FABP7), 874 nM (FABP5) In Vitro:FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury. MCE has not independently confirmed th In Vivo:MF 6 (1mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response. MCE has not independently confirmed the accuracy of these methods. They ar Biological Activity:FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
FABPs ligand 6
CAS number：unknown molecular formula：C28H27FN2O3
overview
compound introduction
Specs
| Chinese alias | FABPs 配体 6 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C28H27FN2O3 |
| molecular weight | 458.52 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
