compound introduction
BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction . BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities. In Vitro:BRD0639 is a first-in-class PBM-competitive small molecule that can support studies of PBM dependent PRMT5 activities and the development of novel PRMT5 inhibitors that selectively target these functions. BRD0639 can engage the cellular target and effecti Biological Activity:BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction . BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities.
