compound introduction
RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely. Appearance:Solid IC50& Target:S1PR1 0.19 nM (EC 50 ) S1PR5 32.8 nM (EC 50 ) In Vitro:RP101988 is a substrate of P-gp and breast cancer resistance protein (BCRP) drug transporters. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely.
