RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflamma IC50& Target:MC4R In Vivo:RO27-3225 (0.012-0.048mg/kg; intravenous injection; Wistar rats) treatment reverses haemorrhagic shock, reduces multiple organ damage and improves survival. RO27-3225 could have a protective role against multiple organ failure following circulatory shock Biological Activity:RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflamma
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RO27-3225 TFA
CAS number：unknown molecular formula：C41H53F3N12O8
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| Chinese alias | RO27-3225 三氟乙酸 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C41H53F3N12O8 |
| molecular weight | 898.93 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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