PDE10A-IN-2 hydrochloride is a potent, highly selective and orally active phosphodiesterase 10A (PDE10A) inhibitor with an IC 50 of 2.8 nM. PDE10A-IN-2 hydrochloride shows selectivity of >3500-fold against other PDE subtypes. PDE10A-IN-2 hydrochloride can Appearance:Solid IC50& Target:PDE10A 2.8 nM (IC 50 ) In Vivo:PDE10A-IN-2 hydrochloride (compound 14 3HCL; 2.5mg/kg; oral administration; daily; for 3 weeks) treatment decreases the typical symptoms of PAH in rats. In Sprague-Dawley rats, the pharmacokinetic study of PDE10A-IN-2 hydrochloride (compound 14 3HCL Biological Activity:PDE10A-IN-2 hydrochloride is a potent, highly selective and orally active phosphodiesterase 10A (PDE10A) inhibitor with an IC 50 of 2.8 nM. PDE10A-IN-2 hydrochloride shows selectivity of >3500-fold against other PDE subtypes. PDE10A-IN-2 hydrochloride can
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PDE10A-IN-2 hydrochloride
CAS number：unknown molecular formula：C33H38Cl3N5O
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| Chinese alias | PDE10A-IN-2盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C33H38Cl3N5O |
| molecular weight | 627.05 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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