compound introduction
MRTX-EX185 formic is a potent inhibitor of GDP-loaded KRAS and KRAS(G12D) , with an IC 50 of 90 nM for KRAS(G12D). MRTX-EX185 formic also binds GDP-loaded HRAS. Appearance:Solid IC50& Target:KRas G12D 90 nM (IC 50 ) Biological Activity:MRTX-EX185 formic is a potent inhibitor of GDP-loaded KRAS and KRAS(G12D) , with an IC 50 of 90 nM for KRAS(G12D). MRTX-EX185 formic also binds GDP-loaded HRAS.
