HS014 TFA is a potent and selective melanocortin-4 (MC4) receptor antagonist, with K i s of 3.16, 108, 54.4 and 694 nM for human MC4, MC1, MC3 and MC5 receptors respectively. HS014 TFA increases food intake in free-feeding rats. Appearance:Solid IC50& Target:MC4R In Vivo:Pretreatment with HS014 TFA blocks the effect of IL-1beta on food intake and respiratory exchange ratio (RER) at later time points (beyond 8 h post injection), as well as the hypoactivity and increases metabolic rate. MCE has not independently confir Biological Activity:HS014 TFA is a potent and selective melanocortin-4 (MC4) receptor antagonist, with K i s of 3.16, 108, 54.4 and 694 nM for human MC4, MC1, MC3 and MC5 receptors respectively. HS014 TFA increases food intake in free-feeding rats .
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HS014 TFA
CAS number：unknown molecular formula：C73H95F3N20O19S2
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| Chinese alias | HS014 三氟乙酸 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C73H95F3N20O19S2 |
| molecular weight | 1677.78 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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