Clanfenur 是一种取代苯甲酰苯脲,是农药灭氟脲的类似物,具有潜在的抗肿瘤活性。Clanfenur 可以与 β-微管蛋白上的秋水仙素结合位点结合,抑制微管聚合,从而阻止肿瘤细胞复制。 Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication .
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Clanfenur
CAS number:51213-99-1 molecular formula:C16H15ClFN3O2
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| Chinese alias | 克兰芬 | N-((4-氯苯基)氨基甲酰基)-2-(二甲基氨基)-6-氟苯甲酰胺 | 克兰氟脲 | ||
| English alias | N-((4-Chlorophenyl)carbamoyl)-2-(dimethylamino)-6-fluorobenzamide | ||
| CAS number | 51213-99-1 | molecular formula | C16H15ClFN3O2 |
| molecular weight | 335.76 g/mol | Exact mass | - |
| PSA | 61.400 Ų | logp | 3.9 |
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