CAS number：1507930-57-5 molecular formula：C55H96N14O13
Gap19 是一种源自 Cx43 细胞质环 (CL) 的九肽，可作为选择性 连接蛋白 43 (Cx43) 半通道阻滞剂。Gap19 在细胞内应用时以 6.5 μM 的 IC50 阻断 Cx43 半通道而不抑制间隙连接 (GJ)。本品为三氟乙酸盐 序列H-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH Product Application Gap19 trifluoroacetate salt has been used to inhibit Ca2+/calmodulin (CaM) gating response of connexin 43 (Cx43) gap junctions.
| Chinese alias | - | ||
| English alias | Gap19 trifluoroacetate salt | KQIEIKKFK trifluoroacetate salt, Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Ly trifluoroacetate salt, L-lLysyl-L-glutaminyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl--L-lysine | ||
| CAS number | 1507930-57-5 | molecular formula | C55H96N14O13 |
| molecular weight | 1161.44 g/mol | Exact mass | 10mM in DMSO |
| PSA | 481.000 Ų | logp | -5.700 |
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