Nintedanib- 13 C,d 3 is the 13 C- and deuterium labeled Nintedanib. Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Appearance:Solid In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar Biological Activity:Nintedanib- 13 C,d 3 is the 13 C- and deuterium labeled Nintedanib. Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
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Nintedanib-13C,d3
CAS number:unknown molecular formula:C3013CH30D3N5O4
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| Chinese alias | 尼达尼布-13C,d3 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C3013CH30D3N5O4 |
| molecular weight | 543.64 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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