CAS number：1562993-37-6 molecular formula：C29H19D8F3N6O
Ponatinib-d 8 is a deuterium labeled Ponatinib. Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2, FGFR1 , and Src , respectively. Form:Solid IC50& Target:c-Kit 12.5 nM (IC 50 ) VEGFR2 1.5 nM (IC 50 ) FGFR1 2.2 nM (IC 50 ) PDGFRα 1.1 nM (IC 50 )
| Chinese alias | 帕奈替尼-d8 | ||
| English alias | - | ||
| CAS number | 1562993-37-6 | molecular formula | C29H19D8F3N6O |
| molecular weight | 540.61 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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