tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling. In Vitro tCFA15 (10 nM-1 μM) dose-dependently affects the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and such effect is via Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures. tCFA15 stimulates arginine Vasotocin secretion in nerve terminals of the neurohypophysis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Oil IC50& Target:Notch1
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tCFA15
CAS number：220757-88-0 molecular formula：C24H44O2
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| Chinese alias | - | ||
| English alias | tCFA15 | 2-Cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- | SCHEMBL580196 | 3-(15-HYDROXYPENTADECYL)-2,4,4-TRIMETHYLCYCLOHEX-2-EN-1-ONE | DTXSID30430917 | HY-104031 | VIA75788 | 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one | 2, | ||
| CAS number | 220757-88-0 | molecular formula | C24H44O2 |
| molecular weight | 364.6 g/mol | Exact mass | ≥99% |
| PSA | 37.300 Ų | logp | 7.900 |
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