Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19. In Vivo In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Imiquimod maleate
CAS number:896106-16-4 molecular formula:C18H20N4O4
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| Chinese alias | 马来酸咪喹莫特 | ||
| English alias | - | ||
| CAS number | 896106-16-4 | molecular formula | C18H20N4O4 |
| molecular weight | 356.38 g/mol | Exact mass | ≥99% |
| PSA | 131.000 Ų | logp | - |
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