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ML-211

CAS number:2205032-89-7    molecular formula:C25H30N4O2

overview

compound introduction

ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) ( IC 50 =17 nM) and LYPLA2 ( IC 50 =30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC 50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases. Form:Solid

Specs

Chinese alias-
English alias-
CAS number2205032-89-7molecular formulaC25H30N4O2
molecular weight418.53 g/molExact mass-
PSA-logp-

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