GNE-375 is a potent and highly selective BRD9 inhibitor with an IC 50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4 , TAF1, and CECR2 . GNE-375 decreases BRD9 binding to chromatin IC50& Target:BRD9 5 nM (IC 50 )
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GNE-375
CAS number:1926989-06-1(DMSO) molecular formula:C25H29N3O5
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1926989-06-1(DMSO) | molecular formula | C25H29N3O5 |
| molecular weight | 451.51 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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