ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain Form:Solid IC50& Target:CB1
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ZCZ011
CAS number:1998197-39-9 molecular formula:C21H18N2O2S
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| Chinese alias | - | ||
| English alias | NSC822447 | NSC-822447 | SCHEMBL17548442 | DTXSID801046384 | 1998197-39-9 | AKOS040749834 | Q27089284 | 6-methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole | ZCZ 011 | GTPL9239 | ZCZ011 | ZCZ-011 | AKOS037652095 | HY-118140 | BDBM50513126 | 6-m | ||
| CAS number | 1998197-39-9 | molecular formula | C21H18N2O2S |
| molecular weight | 362.44 g/mol | Exact mass | ≥99% |
| PSA | 89.900 Ų | logp | 5.3 |
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