compound introduction
PCAF-IN-2 (compound 17) is a potent PCAF inhibitor with an IC 50 value of 5.31 µM. PCAF-IN-2 shows anti-tumour activity. CAF-IN-2 induces apoptosis and arrest the cell cycle at the G2/M phase In Vitro PCAF-IN-2 shows anti-tumour activity with IC 50 s of 3.06, 5.69, 7.56, 2.83 µM for HePG2, MCF-7, PC3, HCT-116 cells, respectively. PCAF-IN-2 (10 µM; 24 h) induces apoptosis and arrest the cell cycle at the G2/M phase in HePG2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PCAF 5.31 μM (IC 50 )
