KDM4-IN-2 (Compound 19a) is a potent and selective KDM4 / KDM5 dual inhibitor with K i s of 4 and 7 nM for KDM4A and KDM5B, respectively Form:Solid IC50& Target:Ki: 4 nM (KDM4A ), 7 nM (KDM5B), IC50: 100±41 nM (KDM4A), 43±21 nM (KDM4B), 38 nM (KDM5B), 123 nM (KDM5C), 4.50 μM (KDM2A), 5.78 μM (KDM3A), 90.22 μM (KDM6B)
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KDM4-IN-2
CAS number:2369607-62-3 molecular formula:C25H26N6O
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2369607-62-3 | molecular formula | C25H26N6O |
| molecular weight | 426.51 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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