compound introduction
(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC 50 of 0.74 μM (+)-Penbutolol is an optical isomer of l-penbutolol with Na + channel-blocking action . In Vitro (+)-penbutolol on the [Ca 2+ ] i -increase induced by LPC is concentration-dependent. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10 -6 M, 5×10 -6 M and 10 -5 M, respectively). MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.74 μM (β-adrenoceptor)
