Azido-PEG4-Amido-Tris 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。Azido-PEG4-Amido-Tris 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 Azido-PEG4-Amido-tri-(carboxyethoxymethyl)-methane is a multi-arm PEG containing an azide group and three hydroxyl groups. The azide group enables Click Chemistry. The indicated molecular weight of the multi-arm PEG is the sum of the molecular weights of all the arms. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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Azido-PEG4-Amido-Tris
CAS number:1398044-55-7 molecular formula:C15H30N4O8
overview
compound introduction
Specs
| Chinese alias | 1-叠氮基-N-(1,3-二羟基-2-(羟甲基)丙-2-基)-3,6,9,12-四氧杂十五烷-15-酰胺 | ||
| English alias | AKOS040741246 | Azido-PEG4-Amido-Tris | 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]propanamide | 3-(2-(2-[2-(2-Azido-ethoxy)-ethoxy]-ethoxy)-ethoxy)-n-(2-hydroxy-1,1-bis-hydroxymethyl-ethyl)-propionamide | ||
| CAS number | 1398044-55-7 | molecular formula | C15H30N4O8 |
| molecular weight | 394.42 g/mol | Exact mass | ≥98% |
| PSA | 141.000 Ų | logp | -2.400 |
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