DBCO-NH-Boc 是一种 PROTAC linker,属于烷基/醚类。可用于合成 PROTAC 分子。DBCO-NH-Boc 是一种点击化学试剂。它含有 DBCO 基团,可以和含有叠氮化物基团的分子发生环张力促进的炔-叠氮环加成反应 (SPAAC)。 DBCO-NH-Boc is a PEG derivative with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions to further react.
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DBCO-NH-Boc
CAS number:1539290-74-8 molecular formula:C23H24N2O3
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester | ||
| CAS number | 1539290-74-8 | molecular formula | C23H24N2O3 |
| molecular weight | 376.45 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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