Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
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Recombinant Mouse TNF RII/TNFRSF1B Protein
CAS number:unknown molecular formula:
overview
compound introduction
Specs
| Chinese alias | 重组小鼠TNF RII/TNFRSF1B蛋白 | 重组小鼠肿瘤坏死因子受体超家族成员1B蛋白 | ||
| English alias | CD120b | Etanercept | p75 TNF receptor | p75 | TBPII | TNFR | soluble TNFR1B variant 1 | TNF RII | CD120b antigen | TNFBR | p80 TNF-alpha receptor | TNF-R2 | TNFR2 | TNFR1B | TNF-R75 | TNFR80 | TNFRII | TNF-RII | TNF-R-II | TNFR-II | TNFRSF1B | tumor necr | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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